Apply to CSU | Barnes, J., Barber, N., Wheatley, D., Williamson, E.M. (2006). Concerns have been expressed about possible interference with the metabolism of the prescription drug Indinivir, but clinical studies have found no evidence for such interference. Current Alzheimer Res., 4(3), 253-62. Because cranberry juice is acidic, it has been suggested that ingestion of large amounts may increase the risk of kidney stone formation. Garlic consumption and cancer prevention: Meta-analyses of colorectal and stomach cancers. Gettman, M., Ogan, K., Brinkley, L., et al. Available at http://www.who.int/mediacentre/factsheets/fs134/en/ last accessed on April 25, 2013. Medicinal properties of echinacea: A critical review. Providing trusted, practical education to help you solve problems, develop skills and build a better future. Maturitas, 57(4), 405.
The herbal market is growing steadily at about 20% each year, and it is estimated that in the United States alone the sale of botanical dietary supplements exceeded $5.3 billion in 2011. Browse a list of dietary supplements and herbal remedies to learn about their effectiveness, safety, and drug interactions. Holistic Nursing Practice, 20(4), 197-203. In general, ginseng is well-tolerated, with adverse reactions largely being mild and reversible (Thompson et al., 2002). For information on how to identify nutrition fraud, see fact sheet. Stay informed by researching the product to determine: safety, validity of claims, dosage, most effective form, plant part, species, time frame of use, side effects, counter indications with other supplements or medications, and reasonable price. There are no known drug/botanical interactions. (2005). Fong, Y.K., Milani, S., Djavan, B. Snitz, B.E., O'Meara, E.S., Carlson, M.C., et al. Acta Pharmacologica Sinica, 26(2), 143-149. (2010). British Journal of Urology International, 93(6), 751-756. Review about Ginkgo biloba special extract EGb 761 (Ginkgo). Herbals and botanicals have the potential to interact with prescription medications, over-the-counter drugs, vitamins and minerals. Top ten most commonly used herbs. Cochrane Database of Systematic Reviews, (12), CD007769. Many consider herbs and botanicals to be natural and therefore healthier and gentler than conventional drugs, even though 30% of all prescription drugs are of herbal origin. This site complies with the HONCode standard for trustworthy health information: Earl E. Bakken Center for Spirituality & Healing, Acupuncture and Traditional Chinese Medicine. Journal of the American Diet. Fertility and Sterility, 87(6), 1243-1249.
Dietary supplements include vitamins, minerals, herbs, amino acids, enzymes, and other substances that may be supplemented, or added to the diet, in order to complete dietary needs or to make up for a nutrition deficiency. A recent Cochrane review also suggests that the herb is as effective as standard antidepressants for major depression. Overall, the study concluded that isoflavones in soy and red clover appear to have a "small but positive" effect and would be beneficial for menopausal women. Office of Dietary Supplements. Effects of garlic supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers. Explore safety concerns about essential oils in supplements and foods. There are no significant contraindications or recognized drug/botanical interactions. Improve age-related memory impairment and dementia: Mild gastrointestinal (GI) upset, headache, dizziness, palpitations, constipation, and allergic skin reactions. More studies need to be done in this area. (2005). While the potential for interactions must remain recognized, the initial concerns are overstated, and the emphasis must remain on "potential.". The HerbList App provides research-based information about the safety and effectiveness of herbal products. Ginkgo biloba special extract in dementia with neuropsychiatric features.
(See the section located above: Are Herbs and Botanicals Safe?). Efficacy and tolerability of Hypericum extract for the treatment of mild to moderate depression. Note that saw palmetto is not effective for the prevention or treatment of prostate cancer. Milk thistle and indinavir: A randomized controlled pharmacokinetics study and meta-analysis. Thomson M, Ali M. (2003). Patients who are preparing for or have undergone organ transplantation should also avoid ginseng. Well tolerated when used in small doses. Questions about CSU Extension programs or resources? The cranberry and the urinary tract. Webmaster | Physical activity also plays an important role in reducing ones risk for disease. There is some uncertainty about the safety of high doses in patients with breast cancer. Reports of severe adverse reactions to ginseng are rare, and many have been associated with the ingestion of excessive doses, which can cause sleeplessness and high blood pressure. Journal of the American Medical Association, 302(24), 2663-2670. The best prescription for disease prevention is a healthy lifestyle. The active ingredients vary depending on the plant part (flower, root, seeds, nuts, bark, branch), plant form (dried, extract, tincture, tea) and plant species. Drug Safety, 25(5), 323-344. What does science say about use of dietary supplements for diabetes? Table 1. These substances are not intended to replace a healthy diet. Avoid herbal therapies if you suffer from certain conditions or under certain circumstances. (2007). A review of the reported case studies, however, concluded that there was sparse evidence for a clinically relevant interaction between cranberry juice ingestion and anticoagulant medicines (Pham & Pham, 2007).
Clinical Infectious Diseases, 35(3), 343. Linde, K. et al. Get information on popular types of herbal supplements, including what they are used for, if they work, and what to avoid. Herbal and botanical supplements are plants used for oral medicinal purposes, and include the flower, leaf, root, and seed of the plant. CSU A-Z Search No: Research finds that it is ineffective or unsafe. Miller, S. C. (2005). Consult them with any questions. Ginkgo biloba for cognitive impairment and dementia. 2007). Click on a botanical to learn how it is used, possible risks and adverse effects, and references. Black cohosh is commonly used to treat menopausal symptoms, especially hot flashes. (2002). Find information and resources for understanding herbal medicine. Two recent Cochrane reviews each focus on a different effect. Many plants contain chemicals called phytoestrogens that have effects similar to human estrogen. However, recent studies indicate that while it does lower serum triglycerides, it does not lower LDL cholesterol. Reinhart, K.M., Talati, R., White, C.M., Coleman, C.I. Bodybuilding and Performance Enhancement Supplements: What You Need To Know, National Center for Complementary and Integrative Health, Botanical Dietary Supplements: Background Information, Apple Cider Vinegar In Dietary Supplements, Consortium for Health and Military Performance. There are some reports of other side effects with doses higher than 160 mg/day, including nausea, vertigo, uterine contractions, and bradycardia. Phytother Res, 19, 314-319. International Journal of Fertility & Women's Medicine, 48(2), 64-8. Current Urology Rep., 7(4), 260. Available at www.consumerlab.com last accessed on April 25, 2013. Lancet Infectious Disease, 7(7), 473-80. Do not take herbal products known to be toxic. Summarizes scientific research on St. Johns wort for depression and suggests sources for more information. In addition to its utility for treating urinary tract infections, cranberry is also used in holistic therapies that focus on the heart. European Journal of Clinical Pharmacology, 61, 1-7. Evaluation of echinacea for the prevention and treatment of the common cold: A meta-analysis. Disclaimer: Information concerning herbals and botanicals is constantly changing; therefore take all herbs with caution. May decrease platelet activity ask pharmacist/doctor before taking with anticoagulant/antiplatelet drugs, garlic, ginko. Garlic can cause smelly breath and body odor.
(2006). Linde, K., Berner, M.M., Kriston, L. (2008). See disclaimer below. Secure .gov websites use HTTPS Part of the difficulty of evaluating these differing outcomes is related to the methods used in each study, such as the selection of the patient populations, length of treatment, dose of medication, and variability in the composition of the treatment medication. (2005). (2009). The Food and Drug Administration (FDA) does not test herbs for safety or efficacy. Find fact sheets with information about specific herbs or botanicalscommon names, what the science says, potential side effects and cautions, and resources for more information. However, there is enough evidence to support the limited use of herbs and botanicals under the guidance of a medical professional. Cranberries and cardiovascular disease risk factors. (2010) for discussions. Markowitz, J.S., Devane, C.L., Chavin, K.D., Taylor, R.M., Ruan, Y., Donovan, J.L. Americans commonly take St. John's wort (Hypericum perforatum) to combat symptoms of depression. Though many herbs are considered safe, some have hazardous side effects especially in children, pregnant women, or those with underlying medical conditions and diseases. The list in this fact sheet may not include all potentially toxic herbs, so check the resources listed in this fact sheet regularly, for additional toxic herbs. A randomised, placebo-controlled, double-blind clinical trial. New England Journal of Medicine, 354(6), 557-566. Yes: Research supports efficacy/safety of this product when used appropriately. Additionally, ginseng should not be used when using large amounts of caffeine or other stimulants. Botanical and dietary supplements for menopausal symptoms: What works, what does not. Current Pharmaceutical Design, 10(3), 261-264. Cochrane Database Syst Rev. The efficacy of St. John's wort in patients with minor depressive symptoms or dysthymia-a double-blind placebo-controlled study. Traditional Medicine. This label does not ensure that doses are similar or that the product is safe, it only provides assurance that the product was properly manufactured and contains the ingredients listed on the label. These and other results support the use of echinacea for prevention and treatment of the common cold. National Institutes of Health: Botanical Dietary Supplements. Milk thistle is most commonly used to support the liver and as a liver protectant. Accumulating evidence indicates that cranberry, as well as other fruits rich in antioxidants, may reduce the risk of cardiovascular disease by increasing the resistance of LDL to oxidation, inhibition of platelet aggregation, reducing blood pressure, and reducing inflammation in circulatory vessels (see McKay and Blumber, 2007). Effect of cranberry juice consumption on urinary stone risk factors. The FDA can then recommend that the product be withdrawn from the market and/or labeled to reflect potential side effects. Other possible effects are heartburn, flatulence, nausea, and diarrhea. Find background information about botanicals and their use, safety, and health benefits as dietary supplements. (2007). Journal of Obstetrics and Gynecology, 104(4), 824-36. Journal of the Society for Integrative Oncology, 4(4), 170-186. National Institutes of Health. Determine whether an herbal supplement is truly needed. Geng, J., Dong, J., Ni, H., et al.
Effect of raw garlic vs. commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia. Herbals and botanicals are sold as dietary supplements and regulated differently than pharmaceutical drugs. Products that pass their tests contain a CL stamp of approval. Garlic: A review of its potential use as an anti-cancer agent. Office of Dietary Supplements. Our physical location is 1311 College Ave, Fort Collins, CO. Read the product label and follow the instructions closely. Herbs are not recommended in place of medical treatment or conventional medicine for chronic conditions or diseases, such as severe depression, diabetes, hypertension, and heart disease. Kim, S.H., Park, K.S., Chang, M.J., Sung, J.H. Gaus, W., Westendorf, J., Diebow, R., Kieser, M. (2005). Schulz, V. (2006). Journal of Nutrition, 133(6), 1983S-1986S. Otherwise, it is generally considered safe. Standardized extracts of St. John's wort have been tested clinically and shown to be an effective alternative to SSRIs or tricyclic antidepressants for the treatment of mild to moderate depression. Cheng, Y., Shen, L.H., Zhang, J.T. See Dekosky et al. Phytoestrogen supplement use by women. Journal of Urology, 172(5 Pt 1), 1792-1799. Siegel, R.K. (1979). Use herbal products only for minor conditions and only on a short-term basis. British Journal of Clinical Pharmacology, 66(4), 444-450. Nahata, M. (2006). Identification of adverse drug reactions by evaluation of a prescription database, demonstrated for "risk of bleeding." Insomnia, anxiety, irritability, gastrointestinal (GI) discomfort, diarrhea, fatigue, dry mouth, dizziness, and headache. Black cohosh may cause mild GI upset. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Krebs, E.E., Ensrud, K.E., MacDonald, R., Wilt, T.J. (2004). Herbal and botanical supplements are the leading type of CAM for both adults and those under the age of 18. Islam, J., Carter, R. (2005). Two recent analyses of clinical studies indicate that garlic extract may be effective for the prevention of stomach and colorectal cancers and is moderately effective in lowering serum cholesterol and triglycerides. (2006). European Journal of Clinical Microbiology & Infectious Disease, 26(11), 767-776. High doses of garlic may enhance the effects and adverse effects of anticoagulant and antiplatelet drugs, including aspirin, clopidogrel (Plavix), enoxaparin (Lovenox), and others. Need expert help on a specific question or topic? American Journal of Health-System Pharmacy, 64(5), 490-494.